Publications
Gamifying cell culture training: The ‘Seru-Otchi’ experience for undergraduates
For novice student researchers, acquiring the necessary specialized knowledge before their initial laboratory experience can be a formidable task. We have developed an educational and interactive virtual cell culture environment to help students learn.
Researchers make major strides toward an all-purpose biosensor chip
“This work is our latest step in developing integrated optofluidic sensing devices that are sensitive enough to detect single biomolecules and work over a very wide range of concentrations,” said Schmidt. “We have shown that this can be done with a single method,...
Braingeneers develop novel method to automate the growth of brain tissue organoids on a chip
Braingeneers develop novel method to automate the growth of brain tissue organoids on a chip The new system can increase reproducibility in cerebral organoid research and shows promise for lowering levels of cellular stress Emily Cerf | UCSC | November 28, 2022 A team...
2024
- Yunjeong Park, Sebastian Hernandez, et al. Modulation of neuronal activity in cortical organoids with bioelectronic delivery of ions and neurotransmitters. Cell. vol 4, issue 1, 100686, January 12, 2024 doi: https://doi.org/10.1016/j.crmeth.2023.100686
- Victoria T. Ly, Drew Ehrlich, et al. Gamifying cell culture training: The ‘Seru-Otchi’ experience for undergraduates. Cell. vol 10, issue 9, E30469, doi;
2023
2022
- Sharf, T., van der Molen, T., Glasauer, S.M.K. et al. Functional neuronal circuitry and oscillatory dynamics in human brain organoids. Nat Commun 13, 4403 (2022). https://doi.org/10.1038/s41467-022-32115-4
- Nowakowski TJ, Salama SR. Cerebral Organoids as an Experimental Platform for Human Neurogenomics. Cells. 2022; 11(18):2803. https://doi.org/10.3390/cells11182803
- Schmitz, MT, Sandoval, K, Chen, CP et al. The development and evolution of inhibitory neurons in primate cerebrum. Nature 603, 871–877 (2022). https://doi.org/10.1038/s41586-022-04510-w
- Seiler ST, Mantalas GL, Selberg J, et al. Modular automated microfluidic cell culture platform reduces glycolytic stress in cerebral cortex organoids. Scientific Reports. 2022;12(1). doi:10.1038/s41598-022-20096-9
2021
- Ly VT, Baudin PV, Pansodtee P, et al. Picroscope: Low-cost system for simultaneous longitudinal biological imaging. Communications Biology. 2021;4(1):1261. doi:10.1038/s42003-021-02779-7.
- Baudin PV, Ly VT, Pansodtee P, et al. Low cost cloud based remote microscopy for Biological Sciences. Internet of Things. 2021:100454. doi:10.1016/j.iot.2021.100454.
- Voitiuk K, Geng J, Keefe MG, et al. Light-weight electrophysiology hardware and software platform for cloud-based neural recording experiments. Journal of Neural Engineering. 2021. doi:10.1101/2021.05.18.444685.
- Parks DF, Voitiuk K, Geng J, et al. Internet of things architecture for high throughput biology. bioRxiv. 2021:453595. doi:10.1101/2021.07.29.453595.
- Popova G, Soliman SS, Kim CN, et al. Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids. Cell Stem Cell. 2021. doi:10.1016/j.stem.2021.08.015.
- Ziffra RS, Kim CN, Ross JM, et al. Single-cell epigenomics reveals mechanisms of human cortical development. Nature. 2021;598(7879):205-213. doi:10.1038/s41586-021-03209-8.
- Bhaduri A, Sandoval-Espinosa C, Otero-Garcia M, et al. An atlas of cortical arealization identifies dynamic molecular signatures. Nature. 2021;598(7879):200-204. doi:10.1038/s41586-021-03910-8.
2020
2019
- Wu C, Selberg J, Nguyen B, Pansodtee P, Jia M, Dechiraju H, Teodorescu M, Rolandi M. A Microfluidic Ion Sensor Array. Small mall 2020, 16, 1906436.
- Strakosas, X., Selberg, J., Pansodtee, P., Yonas, N., Manapongpun, P., Teodorescu, M., & Rolandi, M. (2019). A non-enzymatic glucose sensor enabled by bioelectronic pH control. Scientific reports, 9(1), 10844.
- Fiddes, I. T., Pollen, A. A., Davis, J. M., & Sikela, J. M. (2019). Paired involvement of human-specific Olduvai domains and NOTCH2NL genes in human brain evolution. Human genetics, 1-7.
- Linsley, J. W., Tripathi, A., Epstein, I., Schmunk, G., Mount, E., Campioni, M., … & Samsi, S. (2019). Automated four-dimensional long term imaging enables single cell tracking within organotypic brain slices to study neurodevelopment and degeneration. Communications biology, 2(1), 155.
- Mayer, S., Chen, J., Velmeshev, D., Mayer, A., Eze, U. C., Bhaduri, A., … & Alvarado, B. (2019). Multimodal Single-Cell Analysis Reveals Physiological Maturation in the Developing Human Neocortex. Neuron, 102(1), 143-158.
- Pollen, A. A., Bhaduri, A., Andrews, M. G., Nowakowski, T. J., Meyerson, O. S., Mostajo-Radji, M. A., … & Fiddes, I. T. (2019). Establishing cerebral organoids as models of human-specific brain evolution. Cell, 176(4), 743-756.
- Pai, E. L. L., Vogt, D., Clemente-Perez, A., McKinsey, G. L., Cho, F. S., Hu, J. S., … & Nowakowski, T. J. (2019). Mafb and c-Maf Have Prenatal Compensatory and Postnatal Antagonistic Roles in Cortical Interneuron Fate and Function. Cell reports, 26(5), 1157-1173.
- Adorjan, I., Tyler, T., Bhaduri, A., Demharter, S., Finszter, C. K., Bako, M., … & Kriegstein, A. R. (2019). Neuroserpin expression during human brain development and in adult brain revealed by immunohistochemistry and single cell RNA sequencing. Journal of anatomy.
- Field, A. R., Jacobs, F. M., Fiddes, I. T., Phillips, A. P., Reyes-Ortiz, A. M., LaMontagne, E., … & Hauessler, M. (2019). Structurally Conserved Primate LncRNAs Are Transiently Expressed during Human Cortical Differentiation and Influence Cell-Type-Specific Genes. Stem cell reports, 12(2), 245-257.
2018
- Fiddes, I. T., Lodewijk, G. A., Mooring, M., Bosworth, C. M., Ewing, A. D., Mantalas, G. L., … & Lorig-Roach, R. (2018). Human-specific NOTCH2NL genes affect Notch signaling and cortical neurogenesis. Cell, 173(6), 1356-1369.
- Mostajo-Radji, M. A., & Pollen, A. A. (2018). Physiological Models of Human Neuronal Development and Disease. Neuron, 100(5), 1025-1027.
- Nowakowski, T. J., Rani, N., Golkaram, M., Zhou, H. R., Alvarado, B., Huch, K., … & Petzold, L. R. (2018). Regulation of cell-type-specific transcriptomes by microRNA networks during human brain development. Nature neuroscience, 21(12), 1784.